Campus Chicago Address 676 N St Clair St Suite 1400 CH Telephone +1 312 695 0182 Fax 3126953999 Email

Academic Title Professor Primary Department Department of Medicine, Gastroenterology Division, Feinberg School of Medicine Center Affiliations Cancer Prevention GI Oncology

Publications (17)

Publications
Barrett, TA; Wu, A.; Zhang, H.; Levy, M. S.; Lye, G. J. Microwell engineering characterisation for mammalian cell culture process development. Biotechnol Bioeng (2009) In process.
Brown, J. B.; Lee, G.; Managlia, E.; Grimm, G. R.; Dirisina, R.; Goretsky, T.; Cheresh, P.; Blatner, N. R.; Khazaie, K; Yang, G; Li, L; Barrett, TA 5-ASA inhibits epithelial beta-catenin activation in chronic ulcerative colitis. Gastroenterology (2009) In process.
Benson, A.; Barrett, TA; Sparberg, M.; Buchman, A Efficacy and safety of tacrolimus in refractory ulcerative colitis and Crohn's disease: a single-center experience. Inflamm Bowel Dis (2008) 14:7-12.
Brown, J. B.; Lee, G.; Grimm, G. R.; Barrett, TA Therapeutic benefit of pentostatin in severe IL-10-/- colitis. Inflamm Bowel Dis (2008) 14:880-887.
Gounaris, E.; Tung, C. H.; Restaino, C.; Maehr, R.; Kohler, R.; Joyce, J. A.; Ploegh, H. L.; Barrett, TA; Weissleder, R.; Khazaie, K Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS One (2008) 3:e2916.
He, X. C.; Yin, T.; Grindley, J. C.; Tian, Q.; Sato, T.; Tao, W. A.; Dirisina, R.; Porter-Westpfahl, K. S.; Hembree, M.; Johnson, T.; Wiedemann, L. M.; Barrett, TA; Hood, L.; Wu, H.; Li, L. PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet (2007) 39:189-198.
Budinger, GS; Mutlu, G. M.; Eisenbart, J.; Fuller, A. C.; Bellmeyer, A. A.; Baker, C. M.; Wilson, M.; Ridge, K.; Barrett, TA; Lee, V. Y.; Chandel, N Proapoptotic Bid is required for pulmonary fibrosis. Proc Natl Acad Sci U S A (2006) 103:4604-4609.
Hyun, J. G.; Barrett, TA Oral tolerance therapy in inflammatory bowel disease. Am J Gastroenterol (2006) 101:569-571.
Clayburgh, D. R.; Barrett, TA; Tang, Y.; Meddings, J. B.; Van Eldik, LJ; Watterson, DM; Clarke, L. L.; Mrsny, R. J.; Turner, J. R. Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. J Clin Invest (2005) 115:2702-2715.
Hyun, J. G.; Lee, G.; Brown, J. B.; Grimm, G. R.; Tang, Y.; Mittal, N.; Dirisina, R.; Zhang, Z.; Fryer, J. P.; Weinstock, J. V.; Luster, A. D.; Barrett, TA Anti-interferon-inducible chemokine, CXCL10, reduces colitis by impairing T helper-1 induction and recruitment in mice. Inflamm Bowel Dis (2005) 11:799-805.
Brunelle, J. K.; Santore, M. T.; Budinger, GS; Tang, Y.; Barrett, TA; Zong, W. X.; Kandel, E.; Keith, B.; Simon, M. C.; Thompson, C. B.; Hay, N.; Chandel, N c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. J Biol Chem (2004) 279:4305-4312.
Zhang, Z.; Kaptanoglu, L.; Tang, Y.; Ivancic, D.; Rao, S. M.; Luster, A.; Barrett, TA; Fryer, J. IP-10-induced recruitment of CXCR3 host T cells is required for small bowel allograft rejection. Gastroenterology (2004) 126:809-818.
Haddad, W.; Cooper, C. J.; Zhang, Z.; Brown, J. B.; Zhu, Y.; Issekutz, A.; Fuss, I.; Lee, H. O.; Kansas, GS; Barrett, TA P-selectin and P-selectin glycoprotein ligand 1 are major determinants for Th1 cell recruitment to nonlymphoid effector sites in the intestinal lamina propria. J Exp Med (2003) 198:369-377.
Alnadjim, Z.; Kayali, Z.; Haddad, W.; Holmes, E. W.; Keshavarzian, A.; Mittal, N.; Ivancic, D.; Koehler, R.; Goldsmith, D.; Waltenbaugh, C.; Barrett, TA Differential effects of T-cell activation on gastric and small bowel permeability in alcohol-consuming mice. Alcohol Clin Exp Res (2002) 26:1436-1443.
Lee, H. O.; Cooper, C. J.; Choi, J. H.; Alnadjim, Z.; Barrett, TA The state of CD4+ T cell activation is a major factor for determining the kinetics and location of T cell responses to oral antigen. J Immunol (2002) 168:3833-3838.
Musch, M. W.; Clarke, L. L.; Mamah, D.; Gawenis, L. R.; Zhang, Z.; Ellsworth, W.; Shalowitz, D.; Mittal, N.; Efthimiou, P.; Alnadjim, Z.; Hurst, S. D.; Chang, E. B.; Barrett, TA T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase. J Clin Invest (2002) 110:1739-1747.
Zhang, Z.; Kaptanoglu, L.; Haddad, W.; Ivancic, D.; Alnadjim, Z.; Hurst, S.; Tishler, D.; Luster, A. D.; Barrett, TA; Fryer, J. Donor T cell activation initiates small bowel allograft rejection through an IFN-gamma-inducible protein-10-dependent mechanism. J Immunol (2002) 168:3205-3212.

The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

Khashayarsha Khazaie
Navdeep Chandel
GR Budinger
Linda Van Eldik
Daniel Watterson
Geoffrey Kansas
Guang-Yu Yang
Alan Buchman
Liming Li